Á¦¸ñ ------- ¿øº» ³»¿ë ---------Vitamin K- dependent proteins and anticonvulsant medication. doxycycline tick bite Serious Use Alternative 1 primidone will decrease the level or effect of eliglustat by affecting hepatic intestinal enzyme CYP3A4 metabolism. Vitamin K- dependent proteins and anticonvulsant medication. doxycycline tick bite Serious Use Alternative 1 primidone will decrease the level or effect of eliglustat by affecting hepatic intestinal enzyme CYP3A4 metabolism.